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Clopidogrel Cost Canada

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of costing based on the CMG system for hospitals vary widely across provinces. It was therefore necessary to select a province that provided sufficient detail to make the Clopidogrel cost Canada accurate estimates of costs.

Alberta and Ontario provide case cost data used by the Canadian Institute for Health Information to develop relative weights for CMG classifications; thus, the choice was between these two provinces. Alberta reported data at the most detailed level and was selected as the main source for costing, Clopidogrel Cost Canada.

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Estimates of hospitalization costs were based on the 2003 cost schedules released by the Health Funding and Costing Branch of Alberta Health and Wellness 6. Such an Clopidogrel cost Canada is common in health economic studies 18 and reflects Canadian health economic guideline recommendations. Another limitation of this economic evaluation was the application of Canadian unit costs to resource use from the multinational PLATO study. Canadian participation included 401 patients, Clopidogrel Cost Canada, or 2.

In the absence of long-term data, the model assumed conservatively no extension of treatment Clopidogrel cost Canada beyond 1 year. The approach used to model subsequent events allowed multiple events as utilized in a paper reported by Banerjee et al, 18 including a simplifying assumption such that the model did not allow patients in year 2 onwards to have a subsequent MI if they had previously had a stroke.

Clopidogrel Cost Canada

This assumption was necessary to ensure that patients would not be considered to transition to a Clopidogrel cost Canada health state than post-stroke, and is similar to that employed in a previously published model. These included using average health Clopidogrel cost Canada utilities and costs from the PLATO trial to avoid a potential bias in favor of ticagrelor.

In addition, the base case analysis and the majority of sensitivity analyses utilize the generic cost of clopidogrel, which is the lowest cost treatment option available.

Clopidogrel Cost Canada

Our findings are consistent with those from published PLATO-based ticagrelor cost-effectiveness studies. Conclusion The PLATO trial demonstrated significant reductions in the Clopidogrel cost Canada endpoint of buy Metronidazole death, MI, and stroke over a 1-year period with the use of ticagrelor versus clopidogrel in the Clopidogrel cost Canada of ACS patients, Clopidogrel Cost Canada. Overall, this study strongly supports the reimbursement and use of ticagrelor for the treatment of ACS patients in Canada. Supplementary material Costing methodology The Ontario Case Costing Initiative OCCI provides average costs for hospitalizations and average number of hospital days for various hospitalizations such that an average cost per day can be calculated eg, average cost per day for the treatment of myocardial infarction patients.

In the absence of patient-level data, this method of using an average cost per day combined with the average length of stay in hospital for trial patients for various events allows for a more accurate costing of hospitalizations as observed in the clinical trial as opposed to using the average length of stay for patients in the OCCI database.

However, OCCI does not Clopidogrel cost Canada physician fees billed separately to the Ontario government for minor and major procedures and investigations, and as such these How can i buy Glucotrol 5 mg costing analysis. To avoid double counting of the hospital stay, Clopidogrel Cost Canada, only the additional costs Clopidogrel cost Canada hospital stay were estimated eg, physician fees and applied for each procedure and intervention recorded in the PLATO trial. For each event no event, MI, stroke, or death, the average cost across the two arms of the study was used in the model Table S1.

This average cost per health event was used instead of treatment-specific costing to avoid artificial differences in health event costs between treatment arms that may be caused by normal heterogeneity in resource use between patients.

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